Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.71 |
| ▸ | IDO1 | P14902 | 2/20 | 0.62 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15327070 | 0.83 | NOTUM (1.00) | NOTUMIDO1PIM1SCN4APOLB | |
| SCHEMBL15889913 | 0.79 | NOTUM (0.71) | NOTUMIDO1SCN4APOLBPTPN11 | |
| SCHEMBL1501861 | 0.76 | IDO1 (1.00) | NOTUMIDO1PIM1SCN4ACYP3A4 | |
| SCHEMBL20662101 | 0.76 | NOTUM (0.61) | NOTUMIDO1SCN4APOLBPTPN11 | |
| SCHEMBL8221043 | 0.75 | NOTUM (0.71) | NOTUMIDO1SCN4APOLBPTPN11 | |
| SCHEMBL8281266 | 0.75 | NOTUM (0.71) | NOTUMIDO1SCN4APOLBPTPN11 | |
| SCHEMBL30801577 | 0.75 | NOTUM (0.65) | NOTUMSCN4APOLBPTPN11CYP17A1 | |
| SCHEMBL21414769 | 0.75 | NOTUM (0.65) | NOTUMIDO1SCN4APOLBPTPN11 | |
| SCHEMBL28799614 | 0.75 | NOTUM (0.65) | NOTUMCYP11B1CYP11B2 | |
| SCHEMBL27217106 | 0.75 | NOTUM (0.65) | NOTUMSCN4APOLBPTPN11CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767297-B2 | Compounds for inhibiting TNIK and medical uses thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2023-09-26 | — | — | US | disclosed |
| US-20230039679-A1 | COMPOUNDS FOR INHIBITING TNIK AND MEDICAL USES THEREOF | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767297-B2 | Compounds for inhibiting TNIK and medical uses thereof | TNNI3K, TNK1, TNIK | NOTUM 2557/4885IDO1 2272/4885PIM1 2131/4885 |
| US-20230039679-A1 | COMPOUNDS FOR INHIBITING TNIK AND MEDICAL USES THEREOF | TNNI3K, TNK1, TNIK | NOTUM 2557/4885IDO1 2272/4885PIM1 2131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.