Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | CFTR | P13569 | 8/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | USP1 | O94782 | 1/20 | 0.42 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM6A | O15550 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23976252 | 1.00 | PDE4B (0.47) | PDE4BCFTRTDP1ADORA3KMT2A | |
| SCHEMBL30118572 | 0.86 | NPC1 (0.44) | PDE4BCFTRTDP1ADORA3KMT2A | |
| SCHEMBL23976244 | 0.86 | NPC1 (0.44) | PDE4BCFTRTDP1ADORA3KMT2A | |
| SCHEMBL25313496 | 0.85 | CFTR (0.48) | PDE4BCFTRHIF1AKDM4EKDM6B | |
| SCHEMBL25917192 | 0.85 | CFTR (0.43) | PDE4BCFTRTDP1ADORA3KMT2A | |
| SCHEMBL23976660 | 0.83 | GAA (0.46) | CFTRTDP1ADORA3KMT2ASMN1; SMN2 | |
| SCHEMBL30118845 | 0.83 | GAA (0.46) | CFTRTDP1ADORA3KMT2ASMN1; SMN2 | |
| SCHEMBL30118750 | 0.83 | CFTR (0.45) | PDE4BCFTRTDP1KMT2AHTT | |
| SCHEMBL23976144 | 0.83 | CFTR (0.45) | PDE4BCFTRTDP1KMT2AHTT | |
| SCHEMBL23986876 | 0.82 | CFTR (0.42) | PDE4BCFTRTDP1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4142732-A1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | Global Blood Therapeutics, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |
| EP-4143178-A1 | CYCLOALKYL PYRIMIDINES AS FERROPORTIN INHIBITORS | Global Blood Therapeutics, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |