Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 20/20 | 0.56 |
| ▸ | CRBN | Q96SW2 | 20/20 | 0.56 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | IL1B | P01584 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21106796 | 1.00 | DDB1 (0.56) | DDB1CRBNIKZF3TNFIL1B | |
| Trifluoroacetic Acid SCHEMBL30392145 | 0.92 | CRBN (0.48) | DDB1CRBN | |
| Trifluoroacetic Acid SCHEMBL31726938 | 0.92 | CRBN (0.48) | DDB1CRBN | |
| SCHEMBL31283029 | 0.91 | DDB1 (0.57) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL31282764 | 0.89 | CRBN (0.48) | DDB1CRBN | |
| SCHEMBL31727577 | 0.89 | DDB1 (0.54) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL26101802 | 0.86 | CRBN (0.52) | DDB1CRBNIKZF3 | |
| SCHEMBL21998161 | 0.86 | DDB1 (0.53) | DDB1CRBNIKZF3 | |
| SCHEMBL21760050 | 0.86 | DDB1 (0.63) | DDB1CRBNIKZF3 | |
| SCHEMBL25340273 | 0.84 | DDB1 (0.52) | DDB1CRBNIKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025108411-A1 | EP300/CBP REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 北京沐华生物科技有限责任公司 | 2025-05-30 | — | — | WO | disclosed |
| CN-119013277-A | TYK2 degrading agent and application thereof | 凯麦拉医疗公司 | 2024-11-22 | — | — | CN | disclosed |
| EP-4423086-A1 | TYK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023076161-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| EP-4121043-A1 | MDM2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |