Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.75 |
| ▸ | HSD17B14 | Q9BPX1 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MGAM | O43451 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28234820 | 1.00 | CNR2 (0.75) | CNR2HSD17B14NPC1RAB9AMGAM | |
| SCHEMBL7832199 | 0.86 | CNR2 (1.00) | CNR2HSD17B14NPC1RAB9AMGAM | |
| SCHEMBL30227109 | 0.86 | CNR2 (1.00) | CNR2HSD17B14NPC1RAB9AMGAM | |
| SCHEMBL27838449 | 0.84 | CNR2 (0.96) | CNR2HSD17B14NPC1RAB9AMGAM | |
| SCHEMBL11180845 | 0.83 | CNR2 (1.00) | CNR2HSD17B14NPC1RAB9AMGAM | |
| SCHEMBL11067853 | 0.83 | CNR2 (1.00) | CNR2HSD17B14NPC1RAB9AMGAM | |
| SCHEMBL30227110 | 0.83 | CNR2 (0.72) | CNR2HSD17B14NPC1RAB9AMGAM | |
| SCHEMBL28736550 | 0.82 | CNR2 (0.68) | CNR2HSD17B14NPC1RAB9AMGAM | |
| SCHEMBL1343443 | 0.82 | CNR2 (0.78) | CNR2HSD17B14NPC1RAB9AMGAM | |
| SCHEMBL13475587 | 0.81 | CNR2 (0.72) | CNR2HSD17B14RAB9AMGAMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651752-B | Synthesis method of 2-aroylquinoline derivative | 温州大学 | 2023-02-10 | — | — | CN | disclosed |