SCHEMBL30227224

SCHEMBL30227224

O=C(O)CSC1CCN(c2ccc(Cl)c(C(F)(F)F)c2)C1

nearest known ligand 0.65

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ NOTUM Q6P988 17/20 0.65
▸ DPP4 P27487 2/20 0.49
▸ SLC6A9 P48067 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1410265 1.00 NOTUM (0.65) NOTUMDPP4SLC6A9
SCHEMBL1410444 0.99 NOTUM (0.64) NOTUMDPP4SLC6A9
SCHEMBL30772472 0.89 NOTUM (0.51) NOTUMDPP4
SCHEMBL1410443 0.89 NOTUM (0.59) NOTUMDPP4
SCHEMBL29141955 0.82 NOTUM (0.64) NOTUMDPP4SLC6A9
SCHEMBL29141957 0.81 NOTUM (0.69) NOTUMDPP4SLC6A9
SCHEMBL1410330 0.80 NOTUM (0.59) NOTUMDPP4SLC6A9
SCHEMBL1410617 0.80 NOTUM (0.63) NOTUMSLC6A9
SCHEMBL1409379 0.79 FFAR4 (0.49) NOTUMDPP4
SCHEMBL1410227 0.79 NOTUM (0.66) NOTUMDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120129485-A Methods, compositions, and systems for assessing visual function 英属开曼群岛商倍亮生物有限公司 2025-06-10 — — CN claimed
EP-4507566-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION Belite Bio, Inc (US) 2025-02-19 — — EP claimed
EP-4340701-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION Belite Bio, LLC (US) 2024-03-27 — — EP claimed
CN-117440774-A Biomarkers of age-related macular degeneration 倍亮生物有限责任公司 2024-01-23 — — CN claimed
WO-2023200766-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION BELITE BIO, INC (US) 2023-10-19 — — WO claimed
WO-2022246238-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION BELITE BIO, LLC (US) 2022-11-24 — — WO claimed
CN-120129485-A Methods, compositions, and systems for assessing visual function 英属开曼群岛商倍亮生物有限公司 2025-06-10 — — CN disclosed
EP-4507566-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION Belite Bio, Inc (US) 2025-02-19 — — EP disclosed
EP-4340701-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION Belite Bio, LLC (US) 2024-03-27 — — EP disclosed
CN-117440774-A Biomarkers of age-related macular degeneration 倍亮生物有限责任公司 2024-01-23 — — CN disclosed
WO-2023200766-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION BELITE BIO, INC (US) 2023-10-19 — — WO disclosed
WO-2022246238-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION BELITE BIO, LLC (US) 2022-11-24 — — WO disclosed
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