Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 18/20 | 0.82 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.82 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.82 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.65 |
| ▸ | NAMPT | P43490 | 3/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.65 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24086663 | 1.00 | HDAC1 (0.82) | HDAC1HDAC3HDAC2NCOR2NAMPT | |
| SCHEMBL24086715 | 0.90 | HDAC3 (1.00) | HDAC1HDAC3HDAC2NCOR2NAMPT | |
| SCHEMBL30227098 | 0.90 | HDAC3 (1.00) | HDAC1HDAC3HDAC2NCOR2NAMPT | |
| SCHEMBL30227122 | 0.89 | HDAC3 (0.82) | HDAC1HDAC3HDAC2NCOR2NAMPT | |
| SCHEMBL24086665 | 0.89 | HDAC3 (0.82) | HDAC1HDAC3HDAC2NCOR2NAMPT | |
| SCHEMBL24086662 | 0.88 | HDAC1 (0.79) | HDAC1HDAC3HDAC2NCOR2NAMPT | |
| SCHEMBL31412974 | 0.88 | HDAC1 (0.79) | HDAC1HDAC3HDAC2NCOR2NAMPT | |
| SCHEMBL30227144 | 0.88 | HDAC1 (0.79) | HDAC1HDAC3HDAC2NCOR2NAMPT | |
| SCHEMBL23992208 | 0.87 | HDAC3 (1.00) | HDAC1HDAC3HDAC2NCOR2NAMPT | |
| SCHEMBL30227142 | 0.87 | HDAC3 (1.00) | HDAC1HDAC3HDAC2NCOR2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116033904-A | Histone deacetylase inhibitor for tumor microenvironment immunomodulation | 华上生技医药股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| EP-4142733-A1 | HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT | Great Novel Therapeutics Biotech & Medicals Corporation (TW) | 2023-03-08 | — | — | EP | disclosed |