Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 14/20 | 1.00 |
| ▸ | LCP2 | Q13094 | 5/20 | 1.00 |
| ▸ | RPS6KA2 | Q15349 | 3/20 | 1.00 |
| ▸ | PRKD2 | Q9BZL6 | 3/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23988252 | 1.00 | MAP4K1 (1.00) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL30136142 | 1.00 | MAP4K1 (1.00) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL23987791 | 1.00 | MAP4K1 (1.00) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL30233083 | 0.96 | MAP4K1 (0.92) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL25100154 | 0.96 | MAP4K1 (0.92) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL23987793 | 0.93 | MAP4K1 (1.00) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL25100225 | 0.93 | MAP4K1 (1.00) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL25100179 | 0.93 | MAP4K1 (0.88) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL25100289 | 0.93 | MAP4K1 (0.88) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL30233028 | 0.93 | MAP4K1 (1.00) | MAP4K1LCP2RPS6KA2PRKD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143186-A1 | AZALACTAM COMPOUNDS AS HPK1 INHIBITORS | Pfizer Inc. (US) | 2023-03-08 | — | — | EP | disclosed |