Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | HPGD | P15428 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | IGLV6-57 | P01721 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228596 | 0.91 | IGLV6-57 (0.46) | ALDH1A1HPGDKMT2AMEN1LMNA | |
| SCHEMBL30228423 | 0.88 | IGLV6-57 (0.45) | ALDH1A1HPGDKMT2AMEN1LMNA | |
| SCHEMBL30227869 | 0.87 | IGLV6-57 (0.44) | ALDH1A1HPGDKMT2AMEN1LMNA | |
| SCHEMBL30227937 | 0.84 | IGLV6-57 (0.43) | ALDH1A1HPGDKMT2AMEN1LMNA | |
| SCHEMBL30228113 | 0.84 | IGLV6-57 (0.45) | ALDH1A1HPGDKMT2AMEN1LMNA | |
| SCHEMBL30228289 | 0.84 | IGLV6-57 (0.48) | ALDH1A1HPGDKMT2AMEN1LMNA | |
| SCHEMBL30228149 | 0.84 | IGLV6-57 (0.48) | ALDH1A1HPGDKMT2AMEN1LMNA | |
| SCHEMBL30228253 | 0.84 | IGLV6-57 (0.43) | ALDH1A1HPGDKMT2AMEN1LMNA | |
| SCHEMBL30228135 | 0.83 | IGLV6-57 (0.44) | ALDH1A1HPGDKMT2AMEN1LMNA | |
| SCHEMBL30228273 | 0.83 | IGLV6-57 (0.43) | ALDH1A1HPGDKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |