Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.56 |
| ▸ | CA9 | Q16790 | 4/20 | 0.56 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228335 | 0.88 | IGLV6-57 (0.49) | CA12CA9KCNA3ALDH1A1HPGD | |
| SCHEMBL30228331 | 0.87 | MEN1 (0.43) | CA12CA9ALDH1A1HPGDKDM4E | |
| SCHEMBL30227936 | 0.85 | IGLV6-57 (0.41) | CA12CA9ALDH1A1HPGDKDM4E | |
| SCHEMBL30228353 | 0.85 | AR (0.44) | CA12CA9ALDH1A1HPGDKDM4E | |
| SCHEMBL30228531 | 0.85 | IGLV6-57 (0.41) | CA12CA9ALDH1A1HPGDKDM4E | |
| SCHEMBL30228295 | 0.82 | IGLV6-57 (0.49) | CA12CA9ALDH1A1HPGDKDM4E | |
| SCHEMBL30228447 | 0.81 | KCNA3 (0.44) | CA12CA9KCNA3ALDH1A1HPGD | |
| SCHEMBL30228394 | 0.81 | IGLV6-57 (0.41) | CA12CA9KCNA3ALDH1A1HPGD | |
| SCHEMBL30228269 | 0.79 | IGLV6-57 (0.46) | CA12CA9KCNA3ALDH1A1HPGD | |
| SCHEMBL30228470 | 0.79 | IGLV6-57 (0.48) | CA12CA9KCNA3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |