SCHEMBL30230488

SCHEMBL30230488

COCCOC1CCC(NC(=O)c2nc(Cl)cc3cc[nH]c23)CC1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CD38 P28907 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23329118 1.00 CD38 (0.67) CD38
SCHEMBL22933149 0.84 CD38 (0.67) CD38
SCHEMBL28938326 0.84 CD38 (0.67) CD38
SCHEMBL23329119 0.81 GAA (0.49) CD38
SCHEMBL23329131 0.81 CD38 (0.68) CD38
SCHEMBL28722348 0.81 CD38 (1.00) CD38
SCHEMBL22932649 0.81 CD38 (1.00) CD38
SCHEMBL20612913 0.80 CD38 (0.75) CD38
SCHEMBL17802242 0.80 CD38 (0.75) CD38
SCHEMBL19328304 0.80 CD38 (0.75) CD38

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115697985-B CD38 inhibitors 米托布里奇公司 2025-01-21 CN disclosed
EP-4132919-A1 CD38 INHIBITORS Mitobridge, Inc. (US) 2023-02-15 EP disclosed