SCHEMBL30230489

SCHEMBL30230489

COCCOC1CCC(NC(=O)c2cc(C(F)(F)F)cc(Cl)n2)CC1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CD38 P28907 19/20 0.53
RORC P51449 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25485603 1.00 CD38 (0.53) CD38RORC
SCHEMBL25485488 0.86 CD38 (0.55) CD38
SCHEMBL30261781 0.86 CD38 (0.55) CD38
SCHEMBL30261772 0.85 CD38 (0.54) CD38
SCHEMBL25489082 0.85 CD38 (0.54) CD38
SCHEMBL25490775 0.84 CD38 (0.53) CD38
SCHEMBL30261777 0.84 CD38 (0.53) CD38
SCHEMBL30261825 0.84 CD38 (0.53) CD38
SCHEMBL25485563 0.84 CD38 (0.53) CD38
SCHEMBL25135975 0.82 CD38 (0.77) CD38

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115697985-B CD38 inhibitors 米托布里奇公司 2025-01-21 CN disclosed
EP-4132919-A1 CD38 INHIBITORS Mitobridge, Inc. (US) 2023-02-15 EP disclosed
CN-115697985-A CD38 inhibitors 米托布里奇公司 2023-02-03 CN disclosed