Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700192 | 1.00 | CHRM5 (0.41) | CHRM5CHKACHUKMAPTSMN1; SMN2 | |
| SCHEMBL16701005 | 0.78 | CHRM5 (0.46) | CHRM5CHKACHUKMAPTSMN1; SMN2 | |
| SCHEMBL12497820 | 0.77 | KDM4C (0.39) | MAPTMEN1KMT2AGAA | |
| SCHEMBL8128310 | 0.74 | CHRM5 (0.42) | CHRM5CHKACHUKMAPTSMN1; SMN2 | |
| SCHEMBL5811939 | 0.74 | MAPK10 (0.35) | — | |
| SCHEMBL23836747 | 0.73 | CHRM5 (0.41) | CHRM5CHKACHUKMAPTSMN1; SMN2 | |
| SCHEMBL827969 | 0.73 | CHUK (0.42) | CHRM5CHKACHUKMAPTSMN1; SMN2 | |
| SCHEMBL21100999 | 0.73 | GAA (0.46) | CHRM5CHKACHUKMAPTSMN1; SMN2 | |
| SCHEMBL5700599 | 0.73 | CHRM5 (0.41) | CHRM5CHKACHUKMAPTSMN1; SMN2 | |
| SCHEMBL22180254 | 0.71 | LATS1 (0.43) | LATS1LATS2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547275-A | IL-17A modulators | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |
| EP-4157827-A1 | IL-17A MODULATORS | SANOFI (FR) | 2023-04-05 | — | — | EP | disclosed |