Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | EYA2 | O00167 | 1/20 | 0.70 |
| ▸ | APP | P05067 | 1/20 | 0.70 |
| ▸ | ACE | P12821 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | DRD1 | P21728 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | DRD3 | P35462 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL1413209 | 1.00 | TDP1 (0.70) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL10639065 | 1.00 | TDP1 (0.70) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL10937476 | 0.95 | TDP1 (0.78) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL2471967 | 0.95 | TDP1 (0.78) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL10906870 | 0.95 | TDP1 (0.78) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL668797 | 0.95 | TDP1 (0.78) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL6418284 | 0.95 | TDP1 (0.78) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL357530 | 0.92 | TDP1 (0.82) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL247531 | 0.92 | TDP1 (0.82) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL30569658 | 0.92 | TDP1 (0.82) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3375514-B1 | PROCESS FOR PREPARING STABLE SUSPENSIONS OF METAL NANOPARTICLES | COLOROBBIA ITALIANA SPA (IT) | 2023-08-02 | — | — | EP | claimed |
| CN-115725567-A | Method for rapidly extracting mouse bone tissue DNA by paramagnetic particle method | 江苏康为世纪生物科技股份有限公司 | 2023-03-03 | — | — | CN | claimed |
| CN-115532793-A | Process method for reducing soluble manganese and ammonia nitrogen in electrolytic manganese slag | 梁毅 | 2022-12-30 | — | — | CN | claimed |
| CN-113876995-B | Nanofiber membrane for skin wound and preparation method thereof | 上海交通大学医学院附属第九人民医院 | 2022-12-02 | — | — | CN | claimed |
| CN-114684851-A | Preparation and application of tin dioxide nanoparticles with good dispersibility | 华碧新能源技术研究(苏州)有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-113082295-B | Derived scaffold based on skin-derived acellular matrix and construction method thereof | 大连理工大学 | 2022-06-14 | — | — | CN | claimed |
| CN-113843870-B | Ion-chelating wood preservative treatment method based on weak phase structure enhancement | 中南林业科技大学 | 2022-06-10 | — | — | CN | claimed |
| CN-110961115-B | Catalyst for preparing multi-walled carbon nanotube and preparation method and application thereof | 厦门大学 | 2022-03-29 | — | — | CN | claimed |
| CN-113976147-A | Bi/Bi4O5Br2Photocatalyst, preparation method and application thereof | 汉江师范学院 | 2022-01-28 | — | — | CN | claimed |
| CN-113876995-A | Nanofiber membrane for skin wound and preparation method thereof | 上海交通大学医学院附属第九人民医院 | 2022-01-04 | — | — | CN | claimed |
| CN-112981487-A | Low-energy-consumption quick black aluminum alloy micro-arc oxidation method | 沈阳大学 | 2021-06-18 | — | — | CN | claimed |
| CN-108889296-B | SCR catalyst slurry and preparation method and application thereof | 包头稀土研究院 | 2021-04-02 | — | — | CN | claimed |
| CN-108795429-B | Lutetium lithium fluoride-doped scintillation microcrystal and preparation method and application thereof | 中国科学院福建物质结构研究所 | 2020-11-20 | — | — | CN | claimed |
| CN-108239887-B | Pretreatment method for plate-alignment liquid feeding | 长胜纺织科技发展(上海)有限公司 | 2020-07-31 | — | — | CN | claimed |
| CN-110343125-B | Method for preparing high-purity proportional mixed lithium salt at low cost and application of mixed lithium salt in lithium ion battery | 杉杉新材料（衢州）有限公司 | 2020-07-21 | — | — | CN | claimed |
| CN-110885876-A | Method for quickly extracting, analyzing and identifying DNA outside pen container tree nucleus | 华侨大学 | 2020-03-17 | — | — | CN | claimed |
| EP-3375514-A1 | PROCESS FOR PREPARING STABLE SUSPENSIONS OF METAL NANOPARTICLES AND THE STABLE COLLOIDAL SUSPENSIONS OBTAINED THEREBY | Colorobbia Italia S.p.a. (IT) | 2018-09-19 | — | — | EP | claimed |
| US-9731263-B2 | Process for preparing stable suspensions of metal nanoparticles and the stable colloidal suspensions obtained thereby | COLOROBBIA ITALIA S.P.A. (IT) | 2017-08-15 | — | — | US | claimed |
| EP-2403636-A2 | PROCESS FOR PREPARING STABLE SUSPENSIONS OF METAL NANOPARTICLES AND THE STABLE COLLOIDAL SUSPENSIONS OBTAINED THEREBY | Colorobbia Italia S.p.a. (IT) | 2012-01-11 | — | — | EP | claimed |
| WO-2010100107-A2 | PROCESS FOR PREPARING STABLE SUSPENSIONS OF METAL NANOPARTICLES AND THE STABLE COLLOIDAL SUSPENSIONS OBTAINED THEREBY | COLOROBBIA ITALIA S.P.A. (IT) | 2010-09-10 | — | — | WO | claimed |