Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 15/20 | 0.44 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.43 |
| ▸ | LCP2 | Q13094 | 2/20 | 0.42 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.41 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30232851 | 0.90 | MAP4K1 (0.49) | MAP4K1RPS6KA2PRKD2 | |
| SCHEMBL30233255 | 0.89 | MAP4K1 (0.47) | MAP4K1MAP3K5RPS6KA2PRKD2 | |
| SCHEMBL30233115 | 0.89 | MAP4K1 (0.57) | MAP4K1MAP3K5RPS6KA2PRKD2 | |
| SCHEMBL30233004 | 0.88 | LCP2 (0.56) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL30233057 | 0.88 | MAP4K1 (0.45) | MAP4K1MAP3K5RPS6KA2PRKD2 | |
| SCHEMBL30232929 | 0.87 | MAP4K1 (0.45) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL30233435 | 0.87 | MAP4K1 (0.50) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL30233191 | 0.86 | MAP4K1 (0.49) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL30232948 | 0.86 | MAP4K1 (0.58) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL29261204 | 0.84 | MAP4K1 (0.45) | MAP4K1LCP2RPS6KA2PRKD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023030478-A1 | PYRIDOLACTAM DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-03-09 | — | — | WO | disclosed |