Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30232883 | 0.83 | MAP4K1 (0.33) | PIK3CDPIK3CAPIK3CBPIK3CGPRKD1 | |
| SCHEMBL29261310 | 0.82 | MAP4K1 (0.40) | PIK3CDPIK3CAPIK3CBPIK3CGPRKD1 | |
| SCHEMBL25099928 | 0.82 | PIK3CD (0.37) | PIK3CDPIK3CAPIK3CBPIK3CGPRKD1 | |
| SCHEMBL30233362 | 0.81 | PIK3CD (0.34) | PIK3CDPIK3CAPIK3CBPIK3CGPRKD1 | |
| SCHEMBL21990467 | 0.79 | MAPK1 (0.34) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29261411 | 0.79 | PIK3CD (0.35) | PIK3CDPIK3CAPIK3CBPIK3CGPRKD1 | |
| SCHEMBL29261340 | 0.78 | PIK3CD (0.33) | PIK3CDPIK3CAPIK3CBPIK3CGPRKD1 | |
| SCHEMBL25099922 | 0.77 | PIK3CD (0.35) | PIK3CDPIK3CAPIK3CBPIK3CGPRKD1 | |
| SCHEMBL29261321 | 0.77 | PIK3CD (0.34) | PIK3CDPIK3CAPIK3CBPIK3CGPRKD1 | |
| SCHEMBL29261327 | 0.77 | PIK3CD (0.34) | PIK3CDPIK3CAPIK3CBPIK3CGPRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023030478-A1 | PYRIDOLACTAM DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-03-09 | — | — | WO | disclosed |