Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 15/20 | 0.69 |
| ▸ | LCP2 | Q13094 | 4/20 | 0.69 |
| ▸ | RPS6KA2 | Q15349 | 3/20 | 0.69 |
| ▸ | PRKD2 | Q9BZL6 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30233186 | 1.00 | MAP4K1 (0.69) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL30232814 | 0.93 | MAP4K1 (0.70) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL30233271 | 0.93 | MAP4K1 (0.79) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL30233031 | 0.93 | MAP4K1 (0.79) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL30233137 | 0.92 | MAP4K1 (0.70) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL30233316 | 0.91 | LCP2 (0.78) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL30232777 | 0.90 | MAP4K1 (0.73) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL25100287 | 0.89 | MAP4K1 (0.85) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL25099302 | 0.89 | MAP4K1 (0.85) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL30233073 | 0.89 | MAP4K1 (0.85) | MAP4K1LCP2RPS6KA2PRKD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023030478-A1 | PYRIDOLACTAM DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-03-09 | — | — | WO | disclosed |