Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30233180 | 0.96 | PIK3CD (0.36) | PIK3CDPIK3CBPIK3CGPIK3CAJAK3 | |
| SCHEMBL21990619 | 0.84 | PIK3CD (0.33) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL30227951 | 0.84 | PIK3CD (0.33) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL29261357 | 0.84 | PIK3CD (0.36) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL25099627 | 0.82 | GRM2 (0.33) | JAK3 | |
| SCHEMBL29261271 | 0.80 | — | — | |
| SCHEMBL25099637 | 0.80 | MAP4K1 (0.37) | — | |
| SCHEMBL29261395 | 0.79 | PARP1 (0.31) | — | |
| SCHEMBL21990520 | 0.78 | PIK3CD (0.34) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL25100215 | 0.77 | JAK3 (0.37) | PIK3CDPIK3CBPIK3CGPIK3CAJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023030478-A1 | PYRIDOLACTAM DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-03-09 | — | — | WO | disclosed |