Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 17/20 | 0.76 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27083137 | 1.00 | GRIK1 (0.76) | GRIK1GRIK2MEN1KMT2ALMNA | |
| SCHEMBL30235850 | 0.90 | KMT2A (0.62) | GRIK1GRIK2MEN1KMT2ALMNA | |
| SCHEMBL23831304 | 0.90 | KMT2A (0.62) | GRIK1GRIK2MEN1KMT2ALMNA | |
| SCHEMBL30235184 | 0.90 | GRIK1 (0.60) | GRIK1GRIK2MEN1KMT2ALMNA | |
| SCHEMBL23831311 | 0.90 | GRIK1 (0.73) | GRIK1GRIK2MEN1KMT2ALMNA | |
| SCHEMBL23831236 | 0.90 | GRIK1 (0.60) | GRIK1GRIK2MEN1KMT2ALMNA | |
| SCHEMBL30236093 | 0.90 | GRIK1 (0.73) | GRIK1GRIK2MEN1KMT2ALMNA | |
| SCHEMBL23831414 | 0.89 | GRIK1 (0.59) | GRIK1GRIK2MAPT | |
| SCHEMBL30235733 | 0.89 | GRIK1 (0.59) | GRIK1GRIK2MAPT | |
| SCHEMBL23831180 | 0.88 | GRIK1 (0.76) | GRIK1GRIK2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4120837-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 2-(3-PHENYLUREIDO)BENZAMIDE, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |