Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.54 |
| ▸ | ITPR3 | Q14573 | 6/20 | 0.50 |
| ▸ | ITPR2 | Q14571 | 3/20 | 0.50 |
| ▸ | ITPR1 | Q14643 | 3/20 | 0.50 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.50 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596697 | 0.93 | SMPD1 (0.48) | SMPD1ITPR3ITPR2ITPR1 | |
| SCHEMBL7796118 | 0.93 | SMPD1 (0.48) | SMPD1ITPR3ITPR2ITPR1 | |
| SCHEMBL5381912 | 0.93 | SMPD1 (0.48) | SMPD1ITPR3ITPR2ITPR1 | |
| SCHEMBL5378658 | 0.93 | SMPD1 (0.48) | SMPD1ITPR3ITPR2ITPR1 | |
| SCHEMBL4595256 | 0.93 | SMPD1 (0.48) | SMPD1ITPR3ITPR2ITPR1 | |
| SCHEMBL4442196 | 0.91 | SMPD1 (0.50) | SMPD1ITPR3ITPR2ITPR1INPP5A | |
| SCHEMBL4191662 | 0.91 | SMPD1 (0.50) | SMPD1ITPR3ITPR2ITPR1INPP5A | |
| SCHEMBL7798872 | 0.91 | SMPD1 (0.50) | SMPD1ITPR3ITPR2ITPR1INPP5A | |
| SCHEMBL31076275 | 0.86 | ADORA1 (0.43) | SMPD1ITPR3ITPR2ITPR1 | |
| SCHEMBL31076318 | 0.86 | ADORA1 (0.43) | SMPD1ITPR3ITPR2ITPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11603394-B2 | Targeted effector proteins and uses thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-03-14 | — | — | US | disclosed |