Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 20/20 | 0.79 |
| ▸ | VEGFA | P15692 | 6/20 | 0.79 |
| ▸ | FLT1 | P17948 | 6/20 | 0.79 |
| ▸ | EGLN3 | Q9H6Z9 | 5/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921766 | 1.00 | EGLN1 (0.79) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL30287594 | 0.88 | EGLN1 (1.00) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL1921358 | 0.88 | EGLN1 (1.00) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL1921099 | 0.88 | EGLN1 (1.00) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL1921647 | 0.87 | EGLN1 (1.00) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL14308518 | 0.86 | EGLN1 (0.83) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL1921959 | 0.86 | EGLN1 (0.80) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL30287599 | 0.86 | EGLN1 (0.80) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL1921999 | 0.85 | EGLN1 (0.78) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL1921875 | 0.84 | EGLN1 (1.00) | EGLN1VEGFAFLT1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4095127-A1 | PROLYL HYDROXYLASE INHIBITORS AND METHODS OF USE | Akebia Therapeutics Inc. (US) | 2022-11-30 | — | — | EP | disclosed |