Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 18/20 | 0.83 |
| ▸ | CRBN | Q96SW2 | 18/20 | 0.83 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.63 |
| ▸ | TNF | P01375 | 1/20 | 0.63 |
| ▸ | IL1B | P01584 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29922428 | 0.91 | DDB1 (1.00) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL16209843 | 0.91 | DDB1 (1.00) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL19953931 | 0.91 | DDB1 (1.00) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL26192816 | 0.83 | CRBN (0.77) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL26192246 | 0.83 | CRBN (0.77) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL3655358 | 0.83 | CRBN (0.77) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL3657756 | 0.81 | DDB1 (0.74) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL20845693 | 0.81 | DDB1 (0.73) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL3655019 | 0.80 | DDB1 (0.71) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL3649915 | 0.80 | CRBN (0.71) | DDB1CRBNIKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151635-A1 | COMPOUND BASED ON QUINAZOLINE-SUBSTITUTED GLUTARIMIDE SKELETON AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2023-08-17 | — | — | WO | claimed |
| CN-115666575-A | Compound and use thereof | 福宏治疗公司 | 2023-01-31 | — | — | CN | disclosed |