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SCHEMBL30244841

SCHEMBL30244841

CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCc1cc(Cl)cc(NC(=O)NCc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)c1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 17/20 0.61
▸ DDB1 Q16531 8/20 0.61
▸ GSPT1 P15170 6/20 0.61
▸ IKZF3 Q9UKT9 1/20 0.61
▸ CYP2C19 P33261 1/20 0.53
▸ KCNH2 Q12809 1/20 0.53
▸ CSNK1A1 P48729 4/20 0.42
▸ SALL4 Q9UJQ4 1/20 0.41
▸ STAT3 P40763 1/20 0.40
▸ IKZF2 Q9UKS7 1/20 0.40
▸ WIZ O95785 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30244658 1.00 CRBN (0.61) CRBNDDB1GSPT1IKZF3CYP2C19
SCHEMBL30313063 0.94 CRBN (0.65) CRBNDDB1GSPT1IKZF3CYP2C19
SCHEMBL30313145 0.92 CRBN (0.64) CRBNDDB1GSPT1IKZF3CYP2C19
SCHEMBL30244472 0.91 CRBN (0.62) CRBNDDB1GSPT1IKZF3CYP2C19
SCHEMBL30244510 0.91 CRBN (0.63) CRBNDDB1GSPT1IKZF3CYP2C19
SCHEMBL30313209 0.91 CRBN (0.69) CRBNDDB1GSPT1IKZF3CYP2C19
SCHEMBL30244674 0.90 CRBN (0.58) CRBNDDB1GSPT1IKZF3CYP2C19
SCHEMBL30244546 0.90 CRBN (0.57) CRBNDDB1GSPT1IKZF3CYP2C19
SCHEMBL30244621 0.88 CRBN (0.63) CRBNDDB1GSPT1IKZF3CYP2C19
SCHEMBL30244672 0.88 CRBN (0.63) CRBNDDB1GSPT1IKZF3CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022251588-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO, INC. (US) 2022-12-01 — — WO disclosed