Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 18/20 | 0.49 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3024649 | 1.00 | KCNH2 (0.49) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3024642 | 1.00 | KCNH2 (0.49) | KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL3009283 | 0.99 | KCNH2 (0.48) | KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL3009290 | 0.99 | KCNH2 (0.48) | KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL3009280 | 0.99 | KCNH2 (0.48) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3024723 | 0.87 | KCNH2 (0.54) | KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL3022269 | 0.87 | KCNH2 (0.54) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL13213657 | 0.84 | KCNH2 (0.55) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3021564 | 0.83 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL3021570 | 0.83 | KCNH2 (0.54) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197679-A1 | COMPOUNDS | GLAXO GROUP LIMITED | 2010-08-05 | — | — | US | claimed |
| US-20100197679-A1 | COMPOUNDS | GLAXO GROUP LIMITED | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197679-A1 | COMPOUNDS | NRDC, MRPL21, NISCH | KCNH2 2445/4885KCNQ1 3181/4885CACNA1C 2029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.