Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.50 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.50 |
| ▸ | CHRNG | P07510 | 1/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.50 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | CHRND | Q07001 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Erythro-Hydrobupropion SCHEMBL3320146 | 1.00 | SLC6A4 (0.65) | SLC6A4SLC6A2CYP2C19SLC6A3CHRNA1 | |
| Erythro-Hydrobupropion SCHEMBL29465706 | 1.00 | SLC6A4 (0.65) | SLC6A4SLC6A2CYP2C19SLC6A3CHRNA1 | |
| Erythro-Hydrobupropion SCHEMBL1227545 | 1.00 | SLC6A4 (0.65) | SLC6A4SLC6A2CYP2C19SLC6A3CHRNA1 | |
| Erythro-Hydrobupropion SCHEMBL1226880 | 1.00 | SLC6A4 (0.65) | SLC6A4SLC6A2CYP2C19SLC6A3CHRNA1 | |
| Erythro-Hydrobupropion SCHEMBL1226819 | 1.00 | SLC6A4 (0.65) | SLC6A4SLC6A2CYP2C19SLC6A3CHRNA1 | |
| Erythro-Hydrobupropion SCHEMBL1229064 | 1.00 | SLC6A4 (0.65) | SLC6A4SLC6A2CYP2C19SLC6A3CHRNA1 | |
| Erythro-Hydrobupropion SCHEMBL3320155 | 1.00 | SLC6A4 (0.65) | SLC6A4SLC6A2CYP2C19SLC6A3CHRNA1 | |
| Erythro-Hydrobupropion SCHEMBL3320024 | 1.00 | SLC6A4 (0.65) | SLC6A4SLC6A2CYP2C19SLC6A3CHRNA1 | |
| Erythro-Hydrobupropion SCHEMBL30252231 | 1.00 | SLC6A4 (0.65) | SLC6A4SLC6A2CYP2C19SLC6A3CHRNA1 | |
| Erythro-Hydrobupropion SCHEMBL6429272 | 0.98 | SLC6A4 (0.63) | SLC6A4SLC6A2CYP2C19SLC6A3CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697314-A | Use of bupropion and dextromethorphan combinations for treating neurological disorders | 安泰赛普生物风投二代有限责任公司 | 2023-02-03 | — | — | CN | disclosed |