Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257348 | 1.00 | TSHR (0.32) | TSHR | |
| SCHEMBL3784461 | 0.82 | TSHR (0.41) | TSHR | |
| SCHEMBL1203661 | 0.82 | SLC6A4 (0.31) | TSHR | |
| SCHEMBL9395507 | 0.82 | SLC6A4 (0.31) | TSHR | |
| SCHEMBL1713075 | 0.82 | TSHR (0.50) | TSHR | |
| SCHEMBL6822918 | 0.80 | TSHR (0.35) | TSHR | |
| SCHEMBL30741409 | 0.80 | TSHR (0.35) | TSHR | |
| SCHEMBL22026490 | 0.80 | TSHR (0.35) | TSHR | |
| SCHEMBL6822917 | 0.76 | TSHR (0.32) | TSHR | |
| SCHEMBL11257345 | 0.76 | TSHR (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168398-A1 | TYK-2 INHIBITOR | BeiGene, Ltd. (KY) | 2023-04-26 | — | — | EP | disclosed |
| CN-115715288-A | TYK-2 inhibitors | 百济神州有限公司 | 2023-02-24 | — | — | CN | disclosed |