SCHEMBL30253370

SCHEMBL30253370

O=C1NCCC1=C1CCCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.41
FKBP5 Q13451 1/20 0.39
OR51E2 Q9H255 1/20 0.35
PARP10 Q53GL7 6/20 0.34
PARP1 P09874 5/20 0.34
PARP11 Q9NR21 5/20 0.34
HPGD P15428 3/20 0.34
HTT P42858 1/20 0.34
PDPK1 O15530 1/20 0.34
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
BLM P54132 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 1/20 0.33
PLCG1 P19174 1/20 0.33
APEX1 P27695 1/20 0.33
APOBEC3A P31941 1/20 0.33
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11103726 0.93 CRBN (0.39) CRBNFKBP5OR51E2PARP10PARP1
SCHEMBL16485712 0.88 CRBN (0.39) CRBNFKBP5OR51E2PARP10PARP1
SCHEMBL30497388 0.76 CRBN (0.38) CRBNPARP10PARP1PARP11PDPK1
SCHEMBL10720498 0.75 HPGD (0.34) CRBNFKBP5HPGDHTTMEN1
SCHEMBL13222116 0.73 MAP2K1 (0.62) PARP10PARP1PARP11HPGDHTT
SCHEMBL20155054 0.71 MAP2K1 (0.42) CRBNFKBP5OR51E2PARP10PARP1
SCHEMBL19359650 0.71 MAP2K1 (0.42) CRBNFKBP5OR51E2PARP10PARP1
SCHEMBL24510333 0.67 MEN1 (0.32) CRBNMEN1BLMKMT2A
SCHEMBL116223 0.64
SCHEMBL5464775 0.64 TRIM24 (0.39) HPGDHTTMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112625153-B Catalyst component for olefin polymerization, preparation method, catalyst and application thereof 中国石油化工股份有限公司 2023-03-17 CN disclosed