SCHEMBL30254337

SCHEMBL30254337

N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DPP3 Q9NY33 5/20 0.55
C5AR1 P21730 2/20 0.54
CAPN1 P07384 2/20 0.52
CTSB P07858 2/20 0.52
OPRM1 P35372 2/20 0.51
CTSL P07711 3/20 0.50
CTSS P25774 3/20 0.50
CTSK P43235 3/20 0.50
CTSH P09668 1/20 0.50
NTSR2 O95665 1/20 0.49
NTSR1 P30989 1/20 0.49
SORT1 Q99523 1/20 0.49
CXCR4 P61073 1/20 0.47
ITGB2 P05107 1/20 0.46
ICAM1 P05362 1/20 0.46
ITGAL P20701 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31328327 0.95 C5AR1 (0.57) DPP3C5AR1CAPN1CTSBOPRM1
SCHEMBL30254174 0.95 C5AR1 (0.57) DPP3C5AR1CAPN1CTSBOPRM1
SCHEMBL31328328 0.91 CAPN1 (0.57) DPP3C5AR1CAPN1CTSBCTSL
SCHEMBL30254014 0.91 CAPN1 (0.57) DPP3C5AR1CAPN1CTSBCTSL
SCHEMBL30254065 0.91 CAPN1 (0.59) DPP3C5AR1CAPN1CTSBCTSL
SCHEMBL29677279 0.90 DPP4 (0.48) DPP3C5AR1CAPN1CTSBOPRM1
SCHEMBL29649745 0.90 DPP3 (0.58) DPP3C5AR1CTSLCTSSCTSK
SCHEMBL30618378 0.90 DPP3 (0.60) DPP3C5AR1OPRM1CTSLCTSS
SCHEMBL31674416 0.89 DPP3 (0.59) DPP3C5AR1OPRM1
SCHEMBL31674417 0.89 DPP3 (0.59) DPP3C5AR1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3720873-B1 GLUCAGON-LIKE PEPTIDES IP2IPO INNOVATIONS LTD (GB) 2024-12-04 EP claimed
US-11591380-B2 Glucagon-like peptides IP2IPO INNOVATIONS LIMITED (GB) 2023-02-28 US claimed
EP-3720873-B1 GLUCAGON-LIKE PEPTIDES IP2IPO INNOVATIONS LTD (GB) 2024-12-04 EP disclosed
US-11591380-B2 Glucagon-like peptides IP2IPO INNOVATIONS LIMITED (GB) 2023-02-28 US disclosed