Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727954 | 1.00 | TLR4 (0.33) | TLR4MEN1ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL13910300 | 1.00 | TLR4 (0.33) | TLR4MEN1ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL17067705 | 1.00 | TLR4 (0.33) | TLR4MEN1ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL17067706 | 1.00 | TLR4 (0.33) | TLR4MEN1ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL10028630 | 1.00 | TLR4 (0.33) | TLR4MEN1ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL17067707 | 1.00 | TLR4 (0.33) | TLR4MEN1ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL7741357 | 0.83 | TLR4 (0.35) | TLR4 | |
| SCHEMBL11825966 | 0.81 | TLR4 (0.37) | TLR4 | |
| SCHEMBL29595955 | 0.77 | TLR4 (0.34) | TLR4ALDH1A1 | |
| SCHEMBL29595225 | 0.77 | TLR4 (0.34) | TLR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4402126-A1 | AHR AGONISTS | Eli Lilly and Company (US) | 2024-07-24 | — | — | EP | disclosed |
| CN-118215654-A | AHR agonists | 伊莱利利公司 | 2024-06-18 | — | — | CN | disclosed |
| WO-2023039278-A1 | AHR AGONISTS | ELI LILLY AND COMPANY (US) | 2023-03-16 | — | — | WO | disclosed |