Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24148553 | 1.00 | KDM1A (0.33) | KDM1ADGAT2MAT2ATDO2 | |
| SCHEMBL24148611 | 0.86 | CHRM1 (0.38) | KDM1AMAT2A | |
| SCHEMBL30256440 | 0.86 | CHRM1 (0.38) | KDM1AMAT2A | |
| SCHEMBL30255929 | 0.85 | HRH3 (0.38) | KDM1ADGAT2MAT2ATDO2 | |
| SCHEMBL24148786 | 0.85 | HRH3 (0.38) | KDM1ADGAT2MAT2ATDO2 | |
| SCHEMBL24147825 | 0.85 | ERCC1 (0.36) | KDM1A | |
| SCHEMBL30255950 | 0.85 | ERCC1 (0.36) | KDM1A | |
| SCHEMBL24147817 | 0.82 | MAPKAPK2 (0.33) | KDM1A | |
| SCHEMBL30255570 | 0.82 | MAPKAPK2 (0.33) | KDM1A | |
| SCHEMBL24148166 | 0.80 | CYP3A4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731953-B2 | Methods and compounds for restoring mutant p53 function | PMV PHARMACEUTICALS, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-20230056253-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS, INC. | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230056253-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | TP53, TP53BP1, HRAS | KDM1A 3885/4885DGAT2 2558/4885MAT2A 1108/4885 |
| US-11731953-B2 | Methods and compounds for restoring mutant p53 function | TP53, TP53BP1, HRAS | KDM1A 3885/4885DGAT2 2558/4885MAT2A 1108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.