Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | NSD2 | O96028 | 2/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.31 |
| ▸ | FEN1 | P39748 | 4/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.31 |
| ▸ | PTH1R | Q03431 | 2/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25554329 | 1.00 | CYP19A1 (0.34) | CYP19A1CYP11B1CYP11B2AXLTYRO3 | |
| SCHEMBL30257409 | 0.96 | FEN1 (0.35) | CYP19A1CYP11B1CYP11B2AXLTYRO3 | |
| SCHEMBL25554245 | 0.96 | FEN1 (0.35) | CYP19A1CYP11B1CYP11B2AXLTYRO3 | |
| SCHEMBL25554463 | 0.96 | PTH1R (0.35) | CYP19A1CYP11B1CYP11B2AXLTYRO3 | |
| SCHEMBL25058332 | 0.94 | PDE2A (0.34) | CYP19A1CYP11B1CYP11B2AXLTYRO3 | |
| SCHEMBL30353054 | 0.93 | NSD2 (0.35) | CYP19A1CYP11B1CYP11B2AXLTYRO3 | |
| SCHEMBL25554344 | 0.93 | NSD2 (0.35) | CYP19A1CYP11B1CYP11B2AXLTYRO3 | |
| SCHEMBL25554675 | 0.91 | LRRK2 (0.34) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30257448 | 0.90 | KDM1A (0.36) | CYP19A1CYP11B1CYP11B2AXLTYRO3 | |
| SCHEMBL25554123 | 0.90 | KDM1A (0.36) | CYP19A1CYP11B1CYP11B2AXLTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | claimed |
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |
| EP-4137481-A1 | ARYL OR HETEROARYL DERIVATIVE | Teijin Pharma Limited (JP) | 2023-02-22 | — | — | EP | disclosed |