Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL323068 | 0.77 | USP2 (0.42) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL14924188 | 0.75 | USP2 (0.40) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL18940045 | 0.73 | KDM4E (0.39) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL21798323 | 0.73 | KDM4E (0.39) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL21438159 | 0.73 | KDM4E (0.39) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL4073156 | 0.73 | KDM4E (0.39) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL19263681 | 0.73 | KDM4E (0.39) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL15538067 | 0.73 | KDM4E (0.39) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL14671190 | 0.73 | KDM4E (0.39) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL23142449 | 0.71 | KDM4E (0.37) | ALDH1A1USP2TSHRKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4412994-A1 | JANUS KINASE INHIBITING PYRAZOLE COMPOUNDS AND USES THEREOF | Aerie Pharmaceuticals, Inc. (US) | 2024-08-14 | — | — | EP | disclosed |
| WO-2023060202-A1 | JANUS KINASE INHIBITING PYRAZOLE COMPOUNDS AND USES THEREOF | AERIE PHARMACEUTICALS, INC. (US) | 2023-04-13 | — | — | WO | disclosed |