Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.64 |
| ▸ | PARP1 | P09874 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.62 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | RET | P07949 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TNKS | O95271 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885499 | 1.00 | TNKS2 (0.70) | TNKS2KMT2APDE10APARP1RAB9A | |
| Hydrochloric Acid SCHEMBL2883921 | 0.98 | TNKS2 (0.68) | TNKS2KMT2APDE10APARP1RAB9A | |
| SCHEMBL1914469 | 0.86 | PDE10A (0.69) | TNKS2KMT2APDE10APARP1RAB9A | |
| SCHEMBL31397021 | 0.86 | PDE10A (0.69) | TNKS2KMT2APDE10APARP1RAB9A | |
| SCHEMBL16404338 | 0.85 | PDE10A (0.84) | TNKS2KMT2APDE10APARP1RAB9A | |
| Hydrochloric Acid SCHEMBL15575309 | 0.85 | PDE10A (0.68) | TNKS2KMT2APDE10APARP1RAB9A | |
| SCHEMBL6791216 | 0.83 | PARP1 (0.73) | TNKS2KMT2APDE10APARP1RAB9A | |
| SCHEMBL19673854 | 0.82 | TNKS2 (0.70) | TNKS2KMT2APDE10APARP1RAB9A | |
| SCHEMBL1685046 | 0.82 | TNKS2 (0.70) | TNKS2KMT2APDE10APARP1RAB9A | |
| SCHEMBL3985227 | 0.82 | TNKS2 (0.70) | TNKS2KMT2APDE10APARP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126847-A1 | QUINAZOLINONE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | ENYO Pharma (FR) | 2023-02-08 | — | — | EP | disclosed |