Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 8/20 | 0.46 |
| ▸ | CDK1 | P06493 | 8/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.46 |
| ▸ | CDK9 | P50750 | 6/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.46 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 3/20 | 0.43 |
| ▸ | CCNH | P51946 | 3/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.41 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27784961 | 0.85 | TNNI3K (0.47) | CDK2CDK1CCNB1CCNT1CDK9 | |
| SCHEMBL27763075 | 0.80 | TNNI3K (0.46) | CDK2CDK1CCNB1CCNT1CDK9 | |
| SCHEMBL3028140 | 0.80 | TNNI3K (0.46) | CDK2CDK1CCNB1CCNT1CDK9 | |
| SCHEMBL28780326 | 0.80 | TNNI3K (0.47) | CDK2CDK1CCNB1CCNT1CDK9 | |
| SCHEMBL3023246 | 0.79 | TNNI3K (0.47) | CDK2CDK1CCNB1CCNT1CDK9 | |
| SCHEMBL27763084 | 0.79 | TNNI3K (0.47) | CDK2CDK1CCNB1CCNT1CDK9 | |
| SCHEMBL27763101 | 0.79 | TNNI3K (0.47) | CDK2CDK1CCNB1CCNT1CDK9 | |
| SCHEMBL28780327 | 0.79 | CDK2 (0.67) | CDK2CDK1CCNB1CCNT1CDK9 | |
| SCHEMBL27784926 | 0.78 | CDK1 (0.47) | CDK2CDK1CCNB1CCNT1CDK9 | |
| SCHEMBL23683097 | 0.77 | CDK2 (0.73) | CDK2CDK1CCNB1CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | PALAU PHARMA, S.A. (ES) | 2010-08-12 | — | — | US | disclosed |
| EP-2118105-A1 | PURINE DERIVATIVES | Palau Pharma, S.A. (ES) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008090181-A1 | PURINE DERIVATIVES | PALAU PHARMA, S. A. (ES) | 2008-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | JAK3, JAK1, JAK2 | CDK2 137/4885CDK1 60/4885CCNB1 1478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.