Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3025988 | 1.00 | TDP1 (0.58) | TDP1ALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL14578172 | 0.89 | TDP1 (0.65) | TDP1ALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL14578388 | 0.86 | TDP1 (0.61) | TDP1ALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL14578387 | 0.86 | TDP1 (0.69) | TDP1ALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL14578382 | 0.83 | TDP1 (0.64) | TDP1ALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL6253552 | 0.82 | TDP1 (0.58) | TDP1ALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL3026126 | 0.82 | ATM (0.47) | TDP1ALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL3026122 | 0.82 | ATM (0.47) | TDP1ALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL13215256 | 0.82 | ATM (0.47) | TDP1ALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL3026081 | 0.80 | TDP1 (0.78) | TDP1ALDH1A1HPGDKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572663-B1 | BIPHENYLCARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2013-03-20 | — | — | EP | disclosed |
| EP-1572663-B1 | BIPHENYLCARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2013-03-20 | — | — | EP | disclosed |
| US-20100216849-A1 | BIPHENYLCARBOXAMIDES | DUNKEL RALF | 2010-08-26 | — | — | US | disclosed |
| US-20100216849-A1 | BIPHENYLCARBOXAMIDES | DUNKEL RALF | 2010-08-26 | — | — | US | disclosed |
| US-20100216849-A1 | BIPHENYLCARBOXAMIDES | DUNKEL RALF | 2010-08-26 | — | — | US | disclosed |
| US-7728019-B2 | Biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2010-06-01 | — | — | US | disclosed |
| US-7728019-B2 | Biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2010-06-01 | — | — | US | disclosed |
| US-7728019-B2 | Biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2010-06-01 | — | — | US | disclosed |
| US-20080085924-A1 | Biphenylcaboxamides | BAYER CROPSCINCE AG (DE) | 2008-04-10 | — | — | US | disclosed |
| US-20080085924-A1 | Biphenylcaboxamides | BAYER CROPSCINCE AG (DE) | 2008-04-10 | — | — | US | disclosed |
| US-20080085924-A1 | Biphenylcaboxamides | BAYER CROPSCINCE AG (DE) | 2008-04-10 | — | — | US | disclosed |
| EP-1572663-A1 | BIPHENYLCARBOXAMIDES | Bayer CropScience AG (DE) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004054982-A1 | BIPHENYLCARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2004-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085924-A1 | Biphenylcaboxamides | AHR, Q6ZSR9, DDT | TDP1 2966/4885ALDH1A1 415/4885HPGD 4159/4885 |
| US-20100216849-A1 | BIPHENYLCARBOXAMIDES | AHR, DDT, MRPL21 | TDP1 2686/4885ALDH1A1 478/4885HPGD 4051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.