SCHEMBL30260331

SCHEMBL30260331

Cc1ccccc1C(=O)Nc1ccc(S(=O)(=O)NC(C)CC2CCNCC2)c2ccccc12

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCR8 P51685 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24998101 1.00 CCR8 (0.75) CCR8
SCHEMBL30260252 0.91 CCR8 (0.64) CCR8
SCHEMBL24170888 0.91 CCR8 (0.64) CCR8
SCHEMBL24997776 0.88 CCR8 (0.76) CCR8
SCHEMBL30260259 0.88 CCR8 (0.76) CCR8
SCHEMBL25612650 0.87 CCR8 (0.62) CCR8
SCHEMBL24999099 0.86 CCR8 (1.00) CCR8
SCHEMBL30260380 0.86 CCR8 (1.00) CCR8
SCHEMBL24997826 0.86 CCR8 (1.00) CCR8
SCHEMBL24170133 0.86 CCR8 (1.00) CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4175949-A1 METHODS AND COMPOSITIONS FOR TARGETING TREGS USING CCR8 INHIBITORS Nanjing Immunophage Biotech Co., Ltd. (CN) 2023-05-10 EP claimed
CN-115989223-A Methods and compositions for targeting Tregs using CCR8 inhibitors 南京艾美斐生物医药科技有限公司 2023-04-18 CN claimed
US-12552753-B2 Methods and compositions for targeting Tregs using CCR8 inhibitors NANJING IMMUNOPHAGE BIOMEDICAL CO., LTD. (CN) 2026-02-17 US disclosed
CN-115989223-B Methods and compositions for targeting Tregs using CCR8 inhibitors 南京艾美斐生物医药科技有限公司 2024-09-20 CN disclosed
US-20230159446-A1 Methods and Compositions for Targeting Tregs using CCR8 Inhibitors NANJING IMMUNOPHAGE BIOMEDICAL CO., LTD. (CN) 2023-05-25 US disclosed
EP-4175949-A1 METHODS AND COMPOSITIONS FOR TARGETING TREGS USING CCR8 INHIBITORS Nanjing Immunophage Biotech Co., Ltd. (CN) 2023-05-10 EP disclosed
CN-115989223-A Methods and compositions for targeting Tregs using CCR8 inhibitors 南京艾美斐生物医药科技有限公司 2023-04-18 CN disclosed
US-20230038589-A1 Methods and compositions for targeting Tregs using CCR8 inhibitors Nanjing Immunophage Biotech Co., Ltd. (CN) 2023-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159446-A1 Methods and Compositions for Targeting Tregs using CCR8 Inhibitors CCR8, CCR1, CCR3 CCR8 1/4885
US-12552753-B2 Methods and compositions for targeting Tregs using CCR8 inhibitors CCR8, CCR1, CCR3 CCR8 1/4885
US-20230038589-A1 Methods and compositions for targeting Tregs using CCR8 inhibitors CCR8, CCR1, CCR3 CCR8 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.