Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 13/20 | 0.54 |
| ▸ | CDK12 | Q9NYV4 | 13/20 | 0.54 |
| ▸ | CCNT1 | O60563 | 12/20 | 0.54 |
| ▸ | CDK9 | P50750 | 12/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.54 |
| ▸ | CDK2 | P24941 | 9/20 | 0.54 |
| ▸ | CDK7 | P50613 | 7/20 | 0.52 |
| ▸ | CCNH | P51946 | 7/20 | 0.52 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | ULK1 | O75385 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30260881 | 0.87 | CCNK (0.55) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL30260821 | 0.85 | CCNK (0.54) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL30260964 | 0.85 | CCNK (0.52) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL31666635 | 0.85 | CCNK (0.61) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL31666582 | 0.85 | CCNK (0.61) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL30260884 | 0.83 | CCNK (0.55) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL30261059 | 0.82 | CCNK (0.56) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL30260817 | 0.81 | CCNK (0.52) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL30260946 | 0.80 | CCNK (0.61) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL30260826 | 0.80 | CHEK1 (0.48) | CCNKCDK12CCNT1CDK9CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023040998-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-03-23 | — | — | WO | disclosed |