Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 5/20 | 0.65 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.56 |
| ▸ | CCNK | O75909 | 6/20 | 0.54 |
| ▸ | CDK12 | Q9NYV4 | 6/20 | 0.54 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.54 |
| ▸ | CDK2 | P24941 | 4/20 | 0.54 |
| ▸ | CDK9 | P50750 | 4/20 | 0.54 |
| ▸ | CDK7 | P50613 | 3/20 | 0.53 |
| ▸ | CCNH | P51946 | 3/20 | 0.53 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.53 |
| ▸ | FLT3 | P36888 | 2/20 | 0.52 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.51 |
| ▸ | IDH2 | P48735 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30260876 | 0.89 | CHEK1 (0.58) | ULK1CHEK1CCNKCDK12CCNT1 | |
| SCHEMBL31666582 | 0.87 | CCNK (0.61) | ULK1CHEK1CCNKCDK12CCNT1 | |
| SCHEMBL31666635 | 0.87 | CCNK (0.61) | ULK1CHEK1CCNKCDK12CCNT1 | |
| SCHEMBL30260956 | 0.86 | CCNK (0.57) | ULK1CHEK1CCNKCDK12CCNT1 | |
| SCHEMBL30260884 | 0.84 | CCNK (0.55) | ULK1CHEK1CCNKCDK12CCNT1 | |
| SCHEMBL30260858 | 0.83 | CHEK1 (0.57) | CHEK1CCNKCDK12CCNT1CCNE1 | |
| SCHEMBL30261059 | 0.83 | CCNK (0.56) | ULK1CHEK1CCNKCDK12CCNT1 | |
| SCHEMBL14975888 | 0.82 | SYK (0.71) | CHEK1 | |
| SCHEMBL14975884 | 0.82 | SYK (0.71) | CHEK1 | |
| SCHEMBL30260817 | 0.81 | CCNK (0.52) | ULK1CHEK1CCNKCDK12CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023040998-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-03-23 | — | — | WO | disclosed |