Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 20/20 | 0.86 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16072060 | 0.92 | FGFR4 (1.00) | FGFR4 | |
| SCHEMBL16071576 | 0.92 | FGFR4 (1.00) | FGFR4 | |
| SCHEMBL23653203 | 0.92 | FGFR4 (1.00) | FGFR4 | |
| SCHEMBL16072059 | 0.92 | FGFR4 (1.00) | FGFR4 | |
| SCHEMBL30261972 | 0.90 | FGFR4 (0.75) | FGFR4FGFR2 | |
| SCHEMBL30261956 | 0.90 | FGFR4 (0.75) | FGFR4 | |
| SCHEMBL30261999 | 0.89 | FGFR4 (0.73) | FGFR4 | |
| SCHEMBL30261967 | 0.89 | FGFR4 (0.73) | FGFR4FGFR2 | |
| SCHEMBL16071386 | 0.88 | FGFR4 (0.90) | FGFR4FGFR2 | |
| SCHEMBL24224980 | 0.87 | FGFR4 (1.00) | FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023039828-A1 | FUSED RING COMPOUNDS AS INHIBITORS OF FGFR4 TYROSINE KINASES | NUTSHELL BIOTECH (SHANGHAI) CO., LTD. (CN) | 2023-03-23 | — | — | WO | disclosed |