SCHEMBL30262097

CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)CC(C)C)C(C)C)C(C)C)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)O

nearest known ligand 0.59

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	18/20	0.59

▸	SCTR	P47872	1/20	0.59

▸	KEAP1	Q14145	2/20	0.58

▸	GCGR	P47871	1/20	0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31627888	0.91	GLP1R (0.53)	GLP1RSCTRKEAP1GCGR
SCHEMBL30495584	0.91	GLP1R (0.60)	GLP1RSCTRKEAP1GCGR
SCHEMBL30903289	0.90	GLP1R (0.58)	GLP1RSCTRKEAP1
SCHEMBL30262034	0.89	GLP1R (0.58)	GLP1RSCTRKEAP1GCGR
SCHEMBL29973057	0.89	GLP1R (0.61)	GLP1RSCTR
SCHEMBL30804651	0.89	GLP1R (0.65)	GLP1RSCTRGCGR
SCHEMBL31182538	0.89	GLP1R (0.61)	GLP1RKEAP1
SCHEMBL30974396	0.89	TFPI (0.60)	GLP1RSCTRGCGR
SCHEMBL29526513	0.88	GLP1R (0.57)	GLP1RSCTR
SCHEMBL30495762	0.88	GLP1R (0.69)	GLP1RSCTRGCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230040544-A1	COMPOSITIONS AND METHODS FOR RESTORING AND MAINTAINING THE DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX (DAPC)	SAREPTA THERAPEUTICS, INC.	2023-02-09	—	—	US	disclosed