SCHEMBL30262154

CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)O)C(C)C)[C@@H](C)CC

nearest known ligand 0.71

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	NPY2R	P49146	8/20	0.62

▸	NPY4R	P50391	8/20	0.62

▸	NPY5R	Q15761	8/20	0.62

▸	NPY1R	P25929	6/20	0.62

▸	EP300	Q09472	1/20	0.61

▸	HIF1A	Q16665	1/20	0.61

▸	NMUR2	Q9GZQ4	3/20	0.60

▸	NMUR1	Q9HB89	3/20	0.60

▸	TFPI	P10646	4/20	0.60

▸	MAPK8	P45983	1/20	0.59

▸	MAPK9	P45984	1/20	0.59

▸	MAPK10	P53779	1/20	0.59

▸	RAMP3	O60896	1/20	0.58

▸	CALCR	P30988	1/20	0.58

▸	F2	P00734	1/20	0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31129151	0.91	NPY2R (0.65)	NPY2RNPY4RNPY5RNPY1RNMUR2
SCHEMBL31183026	0.90	NPY2R (0.64)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30974500	0.90	MAPK8 (0.60)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30607487	0.90	NPY2R (0.69)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL29679864	0.90	MAPK8 (0.62)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL31182912	0.90	NPY2R (0.66)	NPY2RNPY4RNPY5RNPY1REP300
Cathelicidin SCHEMBL29350781	0.90	NPY2R (0.65)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL31129149	0.89	NPY2R (0.63)	NPY2RNPY4RNPY5RNPY1RNMUR2
SCHEMBL30883233	0.89	NMUR2 (0.68)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL31462017	0.89	NMUR2 (0.57)	NPY2RNPY4RNPY5RNPY1REP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230040544-A1	COMPOSITIONS AND METHODS FOR RESTORING AND MAINTAINING THE DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX (DAPC)	SAREPTA THERAPEUTICS, INC.	2023-02-09	—	—	US	disclosed