SCHEMBL30262233

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)O)C(C)C

nearest known ligand 0.66

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	4/20	0.64

▸	NPY2R	P49146	7/20	0.64

▸	NPY4R	P50391	7/20	0.64

▸	NPY5R	Q15761	7/20	0.64

▸	NPY1R	P25929	5/20	0.64

▸	TFPI	P10646	2/20	0.62

▸	F2	P00734	4/20	0.62

▸	GLP1R	P43220	1/20	0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29903219	0.95	NPY2R (0.66)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL31182486	0.92	CALCR (0.69)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30495699	0.92	CALCR (0.73)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30932058	0.92	NPY2R (0.68)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30932059	0.92	NPY2R (0.68)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30932056	0.92	NPY2R (0.68)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30932084	0.92	NPY2R (0.68)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL31182495	0.91	NPY2R (0.70)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30198767	0.91	CALCR (0.68)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL29800193	0.91	NPY2R (0.69)	CALCRNPY2RNPY4RNPY5RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230040544-A1	COMPOSITIONS AND METHODS FOR RESTORING AND MAINTAINING THE DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX (DAPC)	SAREPTA THERAPEUTICS, INC.	2023-02-09	—	—	US	disclosed