SCHEMBL30262239

CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)O)C(C)C)[C@@H](C)CC

nearest known ligand 0.56

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	VIPR2	P41587	6/20	0.56

▸	BACE1	P56817	4/20	0.55

▸	BACE2	Q9Y5Z0	3/20	0.55

▸	VIPR1	P32241	4/20	0.55

▸	GLP1R	P43220	4/20	0.53

▸	TFPI	P10646	1/20	0.51

▸	NPY1R	P25929	1/20	0.51

▸	NPY2R	P49146	1/20	0.51

▸	NPY4R	P50391	1/20	0.51

▸	NPY5R	Q15761	1/20	0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29867734	0.88	VIPR1 (0.58)	VIPR2BACE1BACE2VIPR1GLP1R
SCHEMBL30277898	0.87	VIPR2 (0.56)	VIPR2BACE1BACE2VIPR1
SCHEMBL30576973	0.87	GLP1R (0.64)	VIPR1GLP1RTFPINPY1RNPY2R
SCHEMBL31277042	0.87	VIPR2 (0.66)	VIPR2BACE1BACE2VIPR1GLP1R
SCHEMBL38660080	0.86	BACE1 (0.57)	VIPR2BACE1BACE2VIPR1NPY1R
SCHEMBL30512565	0.86	BACE1 (0.54)	BACE1BACE2TFPINPY1RNPY2R
SCHEMBL29520980	0.86	VIPR2 (0.54)	VIPR2BACE1BACE2VIPR1TFPI
SCHEMBL29778027	0.86	VIPR2 (0.54)	VIPR2BACE1BACE2VIPR1TFPI
SCHEMBL29836530	0.86	BACE1 (0.56)	VIPR2BACE1BACE2VIPR1GLP1R
SCHEMBL30844078	0.86	BACE1 (0.59)	VIPR2BACE1BACE2VIPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230040544-A1	COMPOSITIONS AND METHODS FOR RESTORING AND MAINTAINING THE DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX (DAPC)	SAREPTA THERAPEUTICS, INC.	2023-02-09	—	—	US	disclosed