SCHEMBL30263196

SCHEMBL30263196

CNC(=O)c1ccc(N2CCOCC2)cc1-c1nc(-c2ccccc2Cl)cs1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 3/20 0.58
CYP1A1 P04798 2/20 0.58
HTR2C P28335 2/20 0.47
ULK1 O75385 1/20 0.46
PTK2 Q05397 5/20 0.46
INSR P06213 2/20 0.46
IGF1R P08069 2/20 0.46
PTK2B Q14289 2/20 0.46
PKMYT1 Q99640 1/20 0.46
CDK2 P24941 2/20 0.46
CDK5 Q00535 2/20 0.46
CCNA2 P20248 1/20 0.46
CCNA1 P78396 1/20 0.46
CDK5R1 Q15078 1/20 0.46
SLC2A1 P11166 1/20 0.45
CYP1A2 P05177 2/20 0.45
MAPK10 P53779 3/20 0.45
MAPK9 P45984 2/20 0.45
PLK4 O00444 2/20 0.45
CDC7 O00311 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30263215 0.88 CYP1B1 (0.61) CYP1B1CYP1A1HTR2CCDK2CDK5
SCHEMBL30292470 0.85 CYP1B1 (0.54) CYP1B1CYP1A1HTR2CULK1PTK2
SCHEMBL24107424 0.80 CYP1A1 (0.59) CYP1B1CYP1A1HTR2CCYP1A2LRRK2
SCHEMBL30292512 0.80 CYP1A1 (0.59) CYP1B1CYP1A1HTR2CCYP1A2LRRK2
SCHEMBL24107423 0.80 CYP1A1 (0.57) CYP1B1CYP1A1CYP1A2MAPK1MAPK14
SCHEMBL30263242 0.80 CYP1A1 (0.57) CYP1B1CYP1A1CYP1A2MAPK1MAPK14
SCHEMBL24107420 0.78 CYP1B1 (0.57) CYP1B1CYP1A1CYP1A2MAPTNPC1
SCHEMBL30263195 0.78 CYP1A1 (0.47) CYP1B1CYP1A1CDK5CYP1A2JAK2
SCHEMBL24107577 0.78 MAPT (0.55) CYP1B1CYP1A1PTK2INSRIGF1R
SCHEMBL30292516 0.78 MAPT (0.55) CYP1B1CYP1A1PTK2INSRIGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4161921-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-04-12 EP disclosed