Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 5/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30264614 | 0.84 | MAPK7 (0.43) | PIK3CDERBB2MAPK7AURKAACHE | |
| SCHEMBL30126933 | 0.79 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL29834801 | 0.78 | NSD2 (0.54) | EHMT2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL25888785 | 0.75 | PDE4B (0.44) | EHMT2PDE4B | |
| SCHEMBL31654774 | 0.75 | PDE4B (0.44) | EHMT2PDE4B | |
| SCHEMBL27137122 | 0.75 | GRM1 (0.47) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29892098 | 0.75 | GRM1 (0.47) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29686088 | 0.74 | PIK3CD (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGERBB2 | |
| SCHEMBL28983513 | 0.74 | PIK3CD (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGERBB2 | |
| SCHEMBL27118617 | 0.74 | NSD2 (0.49) | EHMT2PDE4BNSD2TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392423-A1 | QUINAZOLINE COMPOUNDS FOR TREATMENT OF DISEASE | Arthrosi Therapeutics, Inc. (US) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023028054-A1 | QUINAZOLINE COMPOUNDS FOR TREATMENT OF DISEASE | ARTHROSI THERAPEUTICS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |