Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SI | P14410 | 1/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MPL | P40238 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220611 | 1.00 | MGAM (0.55) | MGAMGAASIMGAM2HSD17B10 | |
| Bromide SCHEMBL8357485 | 0.98 | MAPT (0.55) | MGAMGAASIMGAM2HSD17B10 | |
| SCHEMBL4755698 | 0.83 | PDE3B (0.51) | MGAMGAASIMGAM2HDAC3 | |
| SCHEMBL6367549 | 0.83 | HDAC3 (0.49) | MGAMGAASIMGAM2HSD17B10 | |
| SCHEMBL30294203 | 0.82 | HDAC3 (0.58) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL3026473 | 0.81 | HDAC3 (0.51) | MGAMGAASIMGAM2HDAC3 | |
| SCHEMBL1206979 | 0.80 | EIF4E (0.65) | RAB9ASMN1; SMN2NPC1EIF4E | |
| SCHEMBL1915932 | 0.79 | KDM1A (0.60) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL9832354 | 0.77 | MGAM (0.59) | MGAMGAASIMGAM2SMN1; SMN2 | |
| SCHEMBL10806812 | 0.77 | HDAC3 (0.68) | MAPTHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661468-A | Dithiazole-containing amide derivative and preparation method and application thereof | 遵义医科大学 | 2025-03-21 | — | — | CN | disclosed |
| CN-115466229-B | Para-amidobenzenesulfonyl compound and application thereof | 上海中医药大学 | 2025-01-24 | — | — | CN | disclosed |
| CN-115466229-A | P-acylamino benzenesulfonyl compound and application thereof | 上海中医药大学 | 2022-12-13 | — | — | CN | disclosed |
| US-8653278-B2 | Isoform selective HDAC inhibitors | GEORGETOWN UNIVERSITY (US) | 2014-02-18 | — | — | US | disclosed |
| US-20100196502-A1 | Isoform Selective HDAC Inhibitors | GEORGETOWN UNIVERSITY (US) | 2010-08-05 | — | — | US | disclosed |
| EP-2049505-A2 | ISOFORM-SELECTIVE HDAC INHIBITORS | Georgetown University (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008019025-A2 | ISOFORM-SELECTIVE HDAC INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2008-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100196502-A1 | Isoform Selective HDAC Inhibitors | HDAC5, HDAC6, HDAC3 | MGAM 4261/4885GAA 343/4885SI 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.