SCHEMBL30264809

SCHEMBL30264809

CC(C)(NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ C5AR1 P21730 1/20 0.49
▸ GLP1R P43220 14/20 0.49
▸ IL23R Q5VWK5 1/20 0.48
▸ MC4R P32245 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30264922 1.00 C5AR1 (0.49) C5AR1GLP1RIL23RMC4R
SCHEMBL30265020 0.95 GLP1R (0.50) C5AR1GLP1RIL23RMC4R
SCHEMBL29511132 0.94 GLP1R (0.51) C5AR1GLP1RMC4R
SCHEMBL30264821 0.94 IL23R (0.52) IL23RMC4R
SCHEMBL30264908 0.92 C5AR1 (0.50) C5AR1IL23RMC4R
SCHEMBL30264812 0.92 C5AR1 (0.50) C5AR1IL23RMC4R
SCHEMBL30264605 0.92 IL23R (0.51) IL23RMC4R
SCHEMBL30264783 0.92 IL23R (0.51) IL23RMC4R
SCHEMBL30264745 0.92 IL23R (0.51) IL23RMC4R
SCHEMBL30264695 0.92 IL23R (0.51) IL23RMC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240391954-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-11-28 — — US disclosed
EP-4392072-A1 MC4R AGONIST PEPTIDES The Regents Of The University Of Michigan (US) 2024-07-03 — — EP disclosed
WO-2023028538-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-03-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391954-A1 MC4R AGONIST PEPTIDES MC4R, MC3R, MC5R C5AR1 1506/4885GLP1R 18/4885IL23R 359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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