SCHEMBL30265017

SCHEMBL30265017

CC(C)(NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 12/20 0.41
▸ NPY1R P25929 6/20 0.41
▸ NPY2R P49146 4/20 0.41
▸ NPY5R Q15761 4/20 0.41
▸ FNTA P49354 6/20 0.35
▸ FNTB P49356 6/20 0.35
▸ PGGT1B P53609 6/20 0.35
▸ DPP7 Q9UHL4 1/20 0.35
▸ PTGS1 P23219 1/20 0.34
▸ GSTK1 Q9Y2Q3 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32690582 0.87 NPY4R (0.46) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL30811126 0.85 NPY4R (0.42) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL31520395 0.85 NPY4R (0.40) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL29658167 0.83 NPY4R (0.45) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL23091326 0.83 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL8067094 0.83 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL21828618 0.83 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL29947092 0.83 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL31097081 0.82 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL29498231 0.81 PTGS1 (0.53) NPY4RNPY1RNPY2RNPY5RFNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240391954-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-11-28 — — US disclosed
EP-4392072-A1 MC4R AGONIST PEPTIDES The Regents Of The University Of Michigan (US) 2024-07-03 — — EP disclosed
WO-2023028538-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-03-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391954-A1 MC4R AGONIST PEPTIDES MC4R, MC3R, MC5R NPY4R 6/4885NPY1R 9/4885NPY2R 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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