Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | PANK3 | Q9H999 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23231761 | 1.00 | CHRM1 (0.52) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL23216903 | 0.86 | CHRM4 (0.55) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL30859934 | 0.85 | CHRM1 (0.56) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL31464881 | 0.83 | PANK3 (0.58) | CHRM1PANK3SIGMAR1TIPARP | |
| SCHEMBL21521550 | 0.83 | PANK3 (0.58) | CHRM1PANK3SIGMAR1TIPARP | |
| SCHEMBL27424684 | 0.82 | RET (0.50) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL27424943 | 0.82 | RET (0.50) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL21522470 | 0.82 | RET (0.50) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL31464957 | 0.82 | RET (0.50) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL30045709 | 0.81 | RET (0.51) | CHRM1CHRM2CHRM4CHRM3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260138987-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | CONTINEUM THERAPEUTICS INC (US) | 2026-05-21 | — | — | US | disclosed |
| US-12565501-B2 | Muscarinic acetylcholine M1 receptor antagonists | CONTINEUM THERAPEUTICS, INC. (US) | 2026-03-03 | — | — | US | disclosed |
| US-20230089921-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | CONTINEUM THERAPEUTICS, INC. | 2023-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12565501-B2 | Muscarinic acetylcholine M1 receptor antagonists | CHRM1, CHRM2, CHRM3 | CHRM1 1/4885CHRM2 2/4885CHRM4 5/4885 |
| US-20230089921-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | CHRM1, CHRM2, CHRM3 | CHRM1 1/4885CHRM2 2/4885CHRM4 5/4885 |
| US-20260138987-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | CHRM1, CHRM5, CHRM3 | CHRM1 1/4885CHRM2 4/4885CHRM4 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.