Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 20/20 | 0.68 |
| ▸ | TLR8 | Q9NR97 | 20/20 | 0.68 |
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20704596 | 1.00 | TLR9 (0.68) | TLR9TLR8TLR7 | |
| SCHEMBL30270175 | 0.90 | TLR9 (0.66) | TLR9TLR8TLR7 | |
| SCHEMBL20704618 | 0.90 | TLR9 (0.66) | TLR9TLR8TLR7 | |
| SCHEMBL20704358 | 0.89 | TLR9 (0.62) | TLR9TLR8TLR7 | |
| SCHEMBL30270171 | 0.89 | TLR9 (0.62) | TLR9TLR8TLR7 | |
| SCHEMBL20704442 | 0.87 | TLR8 (0.67) | TLR9TLR8TLR7 | |
| SCHEMBL30270185 | 0.87 | TLR8 (0.67) | TLR9TLR8TLR7 | |
| SCHEMBL20704554 | 0.86 | TLR9 (0.71) | TLR9TLR8TLR7 | |
| SCHEMBL20704567 | 0.85 | TLR9 (0.64) | TLR9TLR8TLR7 | |
| SCHEMBL30270179 | 0.85 | TLR9 (0.64) | TLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997656-B | Substituted indole compounds useful as TLR7/8/9 inhibitors | 百时美施贵宝公司 | 2023-04-14 | — | — | CN | claimed |
| CN-110997656-B | Substituted indole compounds useful as TLR7/8/9 inhibitors | 百时美施贵宝公司 | 2023-04-14 | — | — | CN | disclosed |