Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENTPD1 | P49961 | 1/20 | 0.57 |
| ▸ | ENTPD2 | Q9Y5L3 | 3/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 3/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3027038 | 1.00 | ENTPD1 (0.57) | ENTPD1ENTPD2ENPP2DGAT2TYMP | |
| SCHEMBL3017927 | 0.90 | ENTPD2 (0.62) | ENTPD1ENTPD2P2RY2 | |
| SCHEMBL3017924 | 0.90 | ENTPD2 (0.62) | ENTPD1ENTPD2P2RY2 | |
| SCHEMBL13211017 | 0.90 | ENTPD1 (0.72) | ENTPD1ENTPD2 | |
| SCHEMBL3025709 | 0.86 | ENTPD1 (0.73) | ENTPD1ENTPD2ENPP2DGAT2P2RY2 | |
| SCHEMBL3025705 | 0.86 | ENTPD1 (0.73) | ENTPD1ENTPD2ENPP2DGAT2P2RY2 | |
| SCHEMBL3024200 | 0.81 | ENTPD1 (0.80) | ENTPD1ENTPD2P2RY2 | |
| SCHEMBL3024202 | 0.81 | ENTPD1 (0.80) | ENTPD1ENTPD2P2RY2 | |
| SCHEMBL13211016 | 0.81 | ENTPD2 (0.78) | ENTPD1ENTPD2 | |
| SCHEMBL13210975 | 0.78 | ENTPD1 (0.91) | ENTPD1ENTPD2P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019834-B1 | ECTONUCLEOTIDASE INHIBITORS | UNIV BONN (DE) | 2014-07-09 | — | — | EP | disclosed |
| US-20100204182-A1 | ECTONUCLEOTIDASE INHIBITORS | RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN (DE) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204182-A1 | ECTONUCLEOTIDASE INHIBITORS | NT5E, NT5C2, ENTPD1 | ENTPD1 3/4885ENTPD2 10/4885ENPP2 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.